Help Page
 Simple search: Get information about a single item (miRNA, gene, process, function, disease, tissue).
 
 Advanced Search: The miRò flexible query composer.

 
 
 
Simple Search:
Choose a category from the menu and specify a single item to be searched by typing or picking it from the list.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Data Mining
Query the database to extract non-trivial subsets of miRNAs sharing some features. The system will compute all the maximal subsets of the specified miRNAs associated to groups of Processes or Broad Phenotypes (Diseases).
 
 
Select up to 5 miRNAs by typing or picking them from the list, or browse all miRNA subsets:
 
miRNAs


Selected miRNAs
 
 
Choose if each subset must contain all the selected miRNAs (AND) or some of them (OR): ANDOR
Choose the miRNA association criteria: ProcessesBroad Phenotypes (Diseases)
 
 
 
 
 
 
 
Customized Search

Enter your personal set of miRNA/target pairs. Your data will be temporarily stored and used in all your session queries. The other users won't be able to see your data. Please enter one pair per row with the following format:
miRNA_name::target_name (e.g. hsa-miR-15a::apex2)
 
Upload a file:
 
Or type your data in the textarea:

Your miRNA/Target
pairs

 
 
 
 
You can browse miRNAs, genes, diseases, ontologies and tissues by clicking one of the following buttons

  
                                                      
 
 
 
Last Update: February, 2009
Resource Version or Release Date Reference

Genetic Association Database December 2008 Becker KG et al. The genetic association database. Nat Genetics 2004;36(5):431-432
Gene Ontology October 2008 Ashburner M et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genetics 2000;25(1):25-29
Mammalian miRNA atlas June 2007 Landgraf P et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007;129(7):1401-14
miRanda September 2008 Release John B et al. Human MicroRNA targets. PLoS Biology 2004;2(11):1862-1879
miRBase v 12.0 (September 2008) Griffiths-Jones S et al. miRBase: tools for microRNA genomics. Nucleic Acids Res 2008;36(Database issue):D154-8
miRecords v 1.0 Xiao F et al. miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res. 2009;37(Database issue):D105-10
NCBI Gene Database September 2008 Maglott D et al. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005; 33(Database Issue):D54–D58
NCBI Nucleotide Database September 2008 Benson DA et al. GenBank. Nucleic Acids Res. 2008; 36(Database issue):D25-30
PicTar 2006 Release Krek A et al. Combinatorial microRNA target predictions. Nat Genetics 2005;37:495-500
TargetScan v 4.2 (April 2008) Lewis BP et al. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005;120:15-20
 
 
 
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